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Optics Express

Optics Express

  • Editor: Andrew M. Weiner
  • Vol. 22, Iss. 8 — Apr. 21, 2014
  • pp: 9764–9773

Measurement of wavefront aberrations and lens deformation in the accommodated eye with optical coherence tomography-equipped wavefront system

Ji C. He and Jianhua Wang  »View Author Affiliations

Optics Express, Vol. 22, Issue 8, pp. 9764-9773 (2014)

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To quantitatively approach the relationship between optical changes in an accommodated eye and the geometrical deformation of its crystalline lens, a long scan-depth anterior segment OCT equipped wavefront sensor was developed and integrated with a Badal system. With this system, accommodation was stimulated up to 6.0D in the left eye and also measured in the same eye for three subjects. High correlations between the accommodative responses of refractive power and the radius of the anterior lens surface were found for the three subjects (r>0.98). The change in spherical aberration was also highly correlated with the change in lens thickness (r>0.98). The measurement was very well repeated at a 2nd measurement session on the same day for the three subjects and after two weeks for one subject. The novelty of incorporating the Badal system into the OCT equipped wavefront sensor eliminated axial misalignment of the measurement system with the test eye due to accommodative vergence, as in the contralateral paradigm. The design also allowed the wavefront sensor to capture conjugated sharp Hartmann-Shack images in accommodated eyes to accurately analyze wavefront aberrations. In addition, this design extended the accommodation range up to 10.0D. By using this system, for the first time, we demonstrated linear relationships of the changes between the refractive power and the lens curvature and also between the spherical aberration and the lens thickness during accommodation in vivo. This new system provides an accurate and useful technique to quantitatively study accommodation.

© 2014 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(330.4460) Vision, color, and visual optics : Ophthalmic optics and devices

ToC Category:
Vision, Color, and Visual Optics

Original Manuscript: February 12, 2014
Revised Manuscript: April 9, 2014
Manuscript Accepted: April 10, 2014
Published: April 16, 2014

Virtual Issues
Vol. 9, Iss. 6 Virtual Journal for Biomedical Optics

Ji C. He and Jianhua Wang, "Measurement of wavefront aberrations and lens deformation in the accommodated eye with optical coherence tomography-equipped wavefront system," Opt. Express 22, 9764-9773 (2014)

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