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Optics Express

Optics Express

  • Editor: J. H. Eberly
  • Vol. 3, Iss. 6 — Sep. 14, 1998
  • pp: 219–229

In vivo video rate optical coherence tomography

Andrew M. Rollins, Manish D. Kulkarni, Siavash Yazdanfar, Rujchai Ung-arunyawee, and Joseph A. Izatt  »View Author Affiliations


Optics Express, Vol. 3, Issue 6, pp. 219-229 (1998)
http://dx.doi.org/10.1364/OE.3.000219


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Abstract

An optical coherence tomography system is described which can image up to video rate. The system utilizes a high power broadband source and real time image acquisition hardware and features a high speed scanning delay line in the reference arm based on Fourier-transform pulse shaping technology. The theory of low coherence interferometry with a dispersive delay line, and the operation of the delay line are detailed and the design equations of the system are presented. Real time imaging is demonstrated in vivo in tissues relevant to early human disease diagnosis (skin, eye) and in an important model in developmental biology (Xenopus laevis).

© Optical Society of America

OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Focus Issue: Optical coherence tomography

History
Original Manuscript: July 24, 1998
Published: September 14, 1998

Citation
Andrew Rollins, Siavash Yazdanfar, Manish Kulkarni, Rujchai Ung-Arunyawee, and Joseph Izatt, "In vivo video rate optical coherence tomography," Opt. Express 3, 219-229 (1998)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-3-6-219


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References

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