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Optics Express

Optics Express

  • Editor: J. H. Eberly
  • Vol. 4, Iss. 11 — May. 24, 1999
  • pp: 449–456

On probing molecular monolayers: a spectroscopic optical waveguide approach of ultra-sensitivity

Sergio B. Mendes and S. Scott Saavedra  »View Author Affiliations


Optics Express, Vol. 4, Issue 11, pp. 449-456 (1999)
http://dx.doi.org/10.1364/OE.4.000449


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Abstract

A broadband, multichannel, single-mode, planar waveguide based spectrometer was developed for probing molecular monolayers. A protein sub-monolayer (thickness h ≅ 3 nm, imaginary part of refractive index kl ≤ 0.01) immobilized on the waveguide surface was characterized by the waveguide attenuated total reflection (ATR) spectrometer. A sensitivity enhancement of 4 orders of magnitude, compared to conventional transmission measurements, has been experimentally achieved in the characterization of ultra-thin films. In addition, polarized spectroscopic measurements at the TE and TM waveguide modes were implemented to determine the average orientation angle of the adsorbed molecules. The work developed here is a new research tool for the investigation of some fundamental aspects of molecular films and a novel platform to develop new technological devices of high sensitivity and selectivity such as biosensors.

© Optical Society of America

OCIS Codes
(240.0240) Optics at surfaces : Optics at surfaces
(240.6690) Optics at surfaces : Surface waves

ToC Category:
Focus Issue: Sensing

History
Original Manuscript: April 5, 1999
Published: May 24, 1999

Citation
Sergio B. Mendes and S. Saavedra, "On probing molecular monolayers: a spectroscopic optical waveguide approach of ultra-sensitivity," Opt. Express 4, 449-456 (1999)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-4-11-449


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References

  1. J. D. Swalen, D. L. Allara, J. D. Andrade, E. A. Chandross, S. Garoff, J. Israelachvili, T. J. McCarthy, R. Murray, R. F. Pease, J. F. Rabolt, K. J. Wynne and H. Yu, "Molecular monolayers and films," Langmuir 3, 932-950 (1987). [CrossRef]
  2. A. N. Parikh and D. L. Allara, "Quantitative determination of molecular structure in multilayer thin films of biaxial and lower symmetry from photon spectroscopies. I. Reflection infrared vibrational spectroscopy," J. Chem. Phys. 96, 927-945 (1992). [CrossRef]
  3. J. D. Andrade and V. Hlady, "Protein adsorption and materials biocompatibility: a tutorial review and suggested hypotheses," Advances in Polymer Science 79, 1-63 (1986). [CrossRef]
  4. O. S. Wolfbeis, "Fiber-optic sensors in biomedical sciences," Pure & Appl. Chem. 59, 663-672 (1987). [CrossRef]
  5. R. E. Dessey, "Waveguides as chemical sensors," Anal. Chem. 61, 1079A-1094A (1989).
  6. M. A. Arnold, "Fiber-optic chemical sensors," Anal. Chem. 64, 1015A-1025A (1992).
  7. S. S. Saavedra and W. M. Reichert, "In situ quantitation of protein adsorption density by integrated optical waveguide attenuated total reflection spectrometry," Langmuir 7, 995-999 (1991). [CrossRef]
  8. T. E. Plowman, M. D. Garrison, D. S. Walker and W. M. Reichert, "Surface sensitivity of SiON integrated optical waveguides (IOWs) examined by IOW-attenuated total reflection spectrometry and IOW-Raman spectroscopy," Thin Solid Films 243, 610-615, (1994). [CrossRef]
  9. J. D. Swalen, M. Tacke, R. Santo, K. E. Rieckoff and J. Fisher, "Spectra of organic molecules in thin films," Helt. Chim. Acta 61, 960-977 (1978). [CrossRef]
  10. D. S. Goldman, P. L. White and N. C. Anheir, "Miniaturized spectrometer employing planar waveguides and grating couplers for chemical analysis," Appl. Opt. 29, 4583-4589 (1990). [CrossRef] [PubMed]
  11. C. Piraud, E. K. Mwarania, J. Yao, K. ODwyer, D. J. Schiffrin and J. S. Wilkinson, "Optoelectrochemical transduction on planar optical waveguides," J. Light. Tech. 10, 693-699 (1992). [CrossRef]
  12. K. Kato, A. Takatsu, N. Matsuda, R. Azumi and M. Matsumoto, "A slab-optical-waveguide absorption spectroscopy of Langmuir-Blodgett films with a white light excitation source," Chem. Lett. 437-438 (1995). [CrossRef]
  13. S. B. Mendes, L. Li, J. J. Burke, J. E. Lee and S. S. Saavedra, "70-nm-bandwidth achromatic waveguide coupler," Appl. Opt. 34, 6180-6186 (1995). [CrossRef] [PubMed]
  14. S. B. Mendes, L. Li, J. J. Burke and S. S. Saavedra, "Achromatic prism-coupler for planar waveguide," Opt. Comm. 136, 320-326 (1997). [CrossRef]
  15. S. B. Mendes, "Broadband attenuated total reflection spectroscopy in the optical waveguide regime," Ph.D. dissertation, University of Arizona, 1997.
  16. L. Li and J. Brazas, "A method for achromatically coupling a beam of light into a waveguide," U.S. patent 5,420,947 (30 May 1995).
  17. S. B. Mendes, L. Li, J. J. Burke, J. E. Lee, D. R. Dunphy and S. S. Saavedra, "Broad-band attenuated total reflection spectroscopy of a hydrated protein film on a single mode planar waveguide," Langmuir 12, 3374- 3376 (1996). [CrossRef]

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