Non-invasive optical mapping of the piglet brain in real time
Optics Express, Vol. 4, Issue 8, pp. 308-314 (1999)
http://dx.doi.org/10.1364/OE.4.000308
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Abstract
We have performed non-invasive, real-time optical mapping of the piglet brain during a subcortical injection of autologous blood. The time resolution of the optical maps is 192 ms, thus allowing us to generate a real-time video of the growing subcortical hematoma. The increased absorption at the site of blood injection is accompanied by a decreased absorption at the contralateral brain side. This contralateral decrease in the optical absorption and the corresponding time traces of the cerebral hemoglobin parameters are consistent with a reduced cerebral blood flow caused by the increased intracranial pressure.
© Optical Society of America
[Optical Society of America ]
OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.5280) Medical optics and biotechnology : Photon migration
ToC Category:
Focus Issue: Biomedical diffuse optical tomography
History
Original Manuscript: March 10, 1999
Published: April 12, 1999
Citation
Sergio Fantini, Maria Franceschini, Enrico Gratton, Dennis Hueber, Warren Rosenfeld, Dev Maulik, Phillip Stubblefield, and Mikjan Stankovic, "Non-invasive optical mapping of the piglet brain in real time," Opt. Express 4, 308-314 (1999)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-4-8-308
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