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Optics Express

Optics Express

  • Editor: J. H. Eberly
  • Vol. 7, Iss. 2 — Jul. 17, 2000
  • pp: 95–106

Multiply scattered light tomography and confocal imaging: detecting neovascularization in age-related macular degeneration

A.E. Elsner, M. Miura, S.A. Burns, E. Beausencourt, C. Kunze, L.M. Kelley, J.P. Walker, G.L. Wing, P.A. Raskauskas, D.C. Fletcher, Q. Zhou, and A.W. Dreher  »View Author Affiliations

Optics Express, Vol. 7, Issue 2, pp. 95-106 (2000)

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A novel technique, Multiply Scattered Light Tomography (MSLT), and confocal Infrared Imaging are used to provide diagnostic information using a comfortable, rapid, and noninvasive method. We investigated these techniques in detecting neovascularization in age-related macular degeneration. The MSLT used a Vertical Cavity Surface Emitting Laser (VCSEL) at 850 nm, while the confocal imaging technique used either the VCSEL or a 790 nm laser diode. Both were implemented into the topographical scanning system (TopSS, Laser Diagnostic Technologies, Inc.) Confocal imaging with both lasers provided different information about neovascularization as a function of focal plane, and different also from MSLT.

© Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(330.4300) Vision, color, and visual optics : Vision system - noninvasive assessment

ToC Category:
Research Papers

Original Manuscript: May 30, 2000
Published: July 17, 2000

Ann Elsner, Masahiro Miura, Stephen Burns, E. Beausencourt, C. Kunze, L. Kelley, J. Walker, G. Wing, P. Raskauskas, D. Fletcher, Qienyuan Zhou, and Andreas Dreher, "Multiply scattered light tomography and confocal imaging: detecting neovascularization in age-related macular degeneration," Opt. Express 7, 95-106 (2000)

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  28. The link to additional figures is http://color.eri.harvard.edu/annhom.htm.
  29. Updates on infrared scanning laser topographic instrumentation are at http://www.laserdiagnostic.com.

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