Three dimensional imaging in age-related macular degeneration

doi:10.1364/OE.9.000436

Optics Express

Editor: J. H. Eberly
Vol. 9, Iss. 9 — Oct. 22, 2001
pp: 436–443

Three dimensional imaging in age-related macular degeneration

Masahiro Miura and Ann Elsner »View Author Affiliations

Optics Express, Vol. 9, Issue 9, pp. 436-443 (2001)
http://dx.doi.org/10.1364/OE.9.000436

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Abstract
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References (13)
Cited By
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Abstract

The ability of confocal scanning laser tomography to quantify the subretinal features was investigated. The slope ratios (anterior slope/posterior slope) of the axial intensity profiles were analyzed. The data from normal subjects showed only minimal influence of individual ocular pigmentation. In the eyes with age-related macular degeneration, the light-tissue interactions vary according to the type of retinal features. Three-dimensional information could be obtained from the axial intensity profiles.

[Optical Society of America ]

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(330.4300) Vision, color, and visual optics : Vision system - noninvasive assessment

ToC Category:
Research Papers

History
Original Manuscript: June 14, 2001
Published: October 22, 2001

Citation
Masahiro Miura and Ann Elsner, "Three dimensional imaging in age-related macular degeneration," Opt. Express 9, 436-443 (2001)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-9-9-436

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References

C. Kunze, A. E. Elsner, E. Beausencourt, L. Moraes, M. E. Hartnett, C. L. Trempe, "Spatial extent of pigment epithelial detachments in age-related macular degeneration," Ophthalmology 106, 1830-40 (1999). [CrossRef] [PubMed]
E. Beausencourt, A. Remky, A. E. Elsner, M. E. Hartnett, C. L. Trempe, "Infrared scanning laser tomography of macular cysts," Ophthalmol. 107, 375-85 (2000). [CrossRef]
M. E. Hartnett, J. Weiter, G. Staurenghi, A. E. Elsner, "Deep retinal vascular anomalous complexes in advanced age-related macular degeneration," Ophthalmol. 103, 2042-2053 (1996).
A. J. Mueller, W. R. Freeman, R. Folberg, D. U. Bartsch, A. Scheider, U. Schaller, A. Kampik, "Evaluation of microvascularization pattern visibility in human choroidal melanomas: comparison of confocal fluorescein with indocyanine green angiography," Graefes Arch. Clin. Exp. Ophthalmol. 237, 448-56 (1999). [CrossRef] [PubMed]
T. J. Holmes, "Blind deconvolution of quantum-limited incoherent imagery: maximum-likelihood approach," J. Opt. Soc. Am. A 9, 1052-61 (1992). [CrossRef] [PubMed]
C. Hudson, J. G. Flanagan, G. S. Turner, D. McLeod, "Scanning laser tomography Z profile signal width as an objective index of macular retinal thickening," Br. J. Ophthalmol. 82, 121-30 (1998). [CrossRef] [PubMed]
M. Miura, A. E. Elsner, E. Beausencourt, C. Kunze, K. Lashkari, M. E. Hartnett, C. L. Trempe, T. Hirose, "Cross-sectional analysis of age-related macular degeneration with confocal scanning laser tomography," Invest. Ophthalmol. Vis. Sci. 41, S162, Abstract Nr: 839 (2000).
A. E. Elsner, M. Miura, S. A. Burns, E. Beausencourt, C. Kunze, L. Kelley, J. Walker, G. P. Wing, P. Raskauskas, D. Fletcher, Q. Zhou, A. W. Dreher, "Multiply scattered light tomography and confocal imaging: detecting neovascularization in age-related macular degeneration," Opt. Express 7, 95-106 (2000), http://www.opticsexpress.org/oearchive/source/22805.htm. [CrossRef] [PubMed]
A. W. Dreher, J. F. Bille, R. N. Weinreb, "Active optical depth resolution improvement of the laser tomographic scanner," Appl. Opt. 28, 804-808 (1989). [CrossRef]
F. C. Delori, K. P. Pflibsen, "Spectral reflectance of the human ocular fundus," Appl. Opt. 28, 1061-1077 (1989). [CrossRef]
A. E. Elsner, S. A. Burns, J. Weiter, F. C. Delori, "Infrared imaging of sub-retinal structures in the human ocular fundus," Vision Res. 36, 191-205 (1996). [CrossRef] [PubMed]
Macular Photocoagulation Study Group, "Five-year follow-up of fellow eyes of patients with age-related macular degeneration and unilateral extrafoveal choroidal neovascularization," Arch. Ophthalmol. 111, 1189-99 (1993). [PubMed]
Macular Photocoagulation Study Group, "Krypton laser photocoagulation for idiopathic neovascular lesions. Results of a randomized clinical trial," Arch. Ophthalmol. 108, 832-37 (1990). [PubMed]

Other

C. Kunze, A. E. Elsner, E. Beausencourt, L. Moraes, M. E. Hartnett, C. L. Trempe, "Spatial extent of pigment epithelial detachments in age-related macular degeneration," Ophthalmology 106, 1830-40 (1999). [CrossRef] [PubMed]
E. Beausencourt, A. Remky, A. E. Elsner, M. E. Hartnett, C. L. Trempe, "Infrared scanning laser tomography of macular cysts," Ophthalmol. 107, 375-85 (2000). [CrossRef]
M. E. Hartnett, J. Weiter, G. Staurenghi, A. E. Elsner, "Deep retinal vascular anomalous complexes in advanced age-related macular degeneration," Ophthalmol. 103, 2042-2053 (1996).
A. J. Mueller, W. R. Freeman, R. Folberg, D. U. Bartsch, A. Scheider, U. Schaller, A. Kampik, "Evaluation of microvascularization pattern visibility in human choroidal melanomas: comparison of confocal fluorescein with indocyanine green angiography," Graefes Arch. Clin. Exp. Ophthalmol. 237, 448-56 (1999). [CrossRef] [PubMed]
T. J. Holmes, "Blind deconvolution of quantum-limited incoherent imagery: maximum-likelihood approach," J. Opt. Soc. Am. A 9, 1052-61 (1992). [CrossRef] [PubMed]
C. Hudson, J. G. Flanagan, G. S. Turner, D. McLeod, "Scanning laser tomography Z profile signal width as an objective index of macular retinal thickening," Br. J. Ophthalmol. 82, 121-30 (1998). [CrossRef] [PubMed]
M. Miura, A. E. Elsner, E. Beausencourt, C. Kunze, K. Lashkari, M. E. Hartnett, C. L. Trempe, T. Hirose, "Cross-sectional analysis of age-related macular degeneration with confocal scanning laser tomography," Invest. Ophthalmol. Vis. Sci. 41, S162, Abstract Nr: 839 (2000).
A. E. Elsner, M. Miura, S. A. Burns, E. Beausencourt, C. Kunze, L. Kelley, J. Walker, G. P. Wing, P. Raskauskas, D. Fletcher, Q. Zhou, A. W. Dreher, "Multiply scattered light tomography and confocal imaging: detecting neovascularization in age-related macular degeneration," Opt. Express 7, 95-106 (2000), http://www.opticsexpress.org/oearchive/source/22805.htm. [CrossRef] [PubMed]
A. W. Dreher, J. F. Bille, R. N. Weinreb, "Active optical depth resolution improvement of the laser tomographic scanner," Appl. Opt. 28, 804-808 (1989). [CrossRef]
F. C. Delori, K. P. Pflibsen, "Spectral reflectance of the human ocular fundus," Appl. Opt. 28, 1061-1077 (1989). [CrossRef]
A. E. Elsner, S. A. Burns, J. Weiter, F. C. Delori, "Infrared imaging of sub-retinal structures in the human ocular fundus," Vision Res. 36, 191-205 (1996). [CrossRef] [PubMed]
Macular Photocoagulation Study Group, "Five-year follow-up of fellow eyes of patients with age-related macular degeneration and unilateral extrafoveal choroidal neovascularization," Arch. Ophthalmol. 111, 1189-99 (1993). [PubMed]
Macular Photocoagulation Study Group, "Krypton laser photocoagulation for idiopathic neovascular lesions. Results of a randomized clinical trial," Arch. Ophthalmol. 108, 832-37 (1990). [PubMed]

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