OSA's Digital Library

Optics Letters

Optics Letters


  • Vol. 25, Iss. 7 — Apr. 1, 2000
  • pp: 463–465

Wavelength-interrogated optical sensor for biochemical applications

M. Wiki and R. E. Kunz  »View Author Affiliations

Optics Letters, Vol. 25, Issue 7, pp. 463-465 (2000)

View Full Text Article

Acrobat PDF (552 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



A novel miniature integrated-optical sensor for versatile multichannel applications is described. Wavelength-modulation techniques using laser diodes (vertical-cavity surface-emitting lasers) are used to interrogate multiple-waveguide sensing regions on a single integrated-optical chip for accurate measurement of effective refractive-index changes at a high data rate. With the experimental miniature sensor system, a resolution of ΔNPP = 10-7 (short term, peak to peak) of the effective refractive index was demonstrated. In terms of surface-mass coverage, this resolution corresponds to ΔΓPP = 130 fg/mm2.

© 2000 Optical Society of America

OCIS Codes
(050.2770) Diffraction and gratings : Gratings
(130.2790) Integrated optics : Guided waves
(130.6010) Integrated optics : Sensors
(130.6750) Integrated optics : Systems
(140.3600) Lasers and laser optics : Lasers, tunable

M. Wiki and R. E. Kunz, "Wavelength-interrogated optical sensor for biochemical applications," Opt. Lett. 25, 463-465 (2000)

Sort:  Author  |  Year  |  Journal  |  Reset


  1. BIOS-1 input grating-coupler instrument, Artificial Sensing Instruments AG, Zurich Switzerland.
  2. J. Dübendorfer and R. E. Kunz, Appl. Opt. 37, 1890 (1998).
  3. R. Karlsson and R. Stahlberg, Anal. Biochem. 228, 274 (1995).
  4. BIAcore and BIAlite surface-plasmon resonance biosensors; Biocore, Uppsala, Sweden.
  5. R. Cush, J. M. Cronin, W. J. Stewart, C. H. Maule, J. Molloy, and N. J. Goddard, Biosensors Bioelectron. 8, 347 (1993).
  6. IAsys resonant mirror biosensor sytem, Affinity Sensors, Cambridge, UK.
  7. W. Lukosz, Ch. Stamm, H. R. Moser, R. Ryf, and J. Dübendorfer, Sensors Actuators B 31, 203 (1996).
  8. R. G. Heideman, R. P. H. Kooyman, and J. Greve, Sensors Actuators B 10, 209 (1993).
  9. A. Brandenburg, Sensors Actuators B 38–39, 266 (1997).
  10. J. Dübendorfer and R. E. Kunz, Sensors Actuators B 38–39, 116 (1996).
  11. K. Gulden, M. Moser, and S. Lüscher, Proc. SPIE 2682, 125 (1996).
  12. Ph. M. Nellen and W. Lukosz, Sensors Actuators B 1, 592 (1990).
  13. R. E. Kunz, Sensors Actuators B 11, 167 (1993).
  14. Europlex 99510, Roehm Darmstadt, Germany.
  15. R. E. Kunz, J. Edlinger, P. Sixt, and M. T. Gale, Sensors Actuators A 47, 482 (1995).
  16. BPY 11P, Siemens Munich, Germany.
  17. LIA-BVD-150-H, Femto, Berlin.

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited