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Optics Letters

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  • Vol. 28, Iss. 14 — Jul. 15, 2003
  • pp: 1230–1232

Fourier-domain low-coherence interferometry for light-scattering spectroscopy

Adam Wax, Changhuei Yang, and Joseph A. Izatt  »View Author Affiliations


Optics Letters, Vol. 28, Issue 14, pp. 1230-1232 (2003)
http://dx.doi.org/10.1364/OL.28.001230


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Abstract

We present a novel method for obtaining depth-resolved spectra for determining scatterer size through elastic-scattering properties. Depth resolution is achieved with a white-light source in a Michelson interferometer with the mixed signal and reference fields dispersed by a spectrograph. The spectrum is Fourier transformed to yield the axial spatial cross correlation between the signal and reference fields with near 1-µm depth resolution. Spectral information is obtained by windowing to yield the scattering amplitude as a function of wave number. The technique is demonstrated by determination of the size of polystyrene microspheres in a subsurface layer with subwavelength accuracy. Application of the technique to probing the size of cell nuclei in living epithelial tissues is discussed.

© 2003 Optical Society of America

OCIS Codes
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(290.1350) Scattering : Backscattering

Citation
Adam Wax, Changhuei Yang, and Joseph A. Izatt, "Fourier-domain low-coherence interferometry for light-scattering spectroscopy," Opt. Lett. 28, 1230-1232 (2003)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-28-14-1230


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References

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