In vivo measurement of the local optical properties of tissue by use of differential path-length spectroscopy
Optics Letters, Vol. 29, Issue 10, pp. 1087-1089 (2004)
http://dx.doi.org/10.1364/OL.29.001087
Acrobat PDF (289 KB)
Abstract
We demonstrate the capability of differential path-length spectroscopy (DPS) to determine the local optical properties of tissue in vivo. DPS measurements on bronchial mucosa are analyzed and yield information on the local blood oxygenation, blood content, average microvessel diameter, and wavelength dependence of the reduced scattering coefficient. Our data collected to date show that cancerous bronchial mucosa has a lower capillary oxygenation and a larger average capillary diameter than normal bronchial mucosa.
© 2004 Optical Society of America
OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(170.7050) Medical optics and biotechnology : Turbid media
Citation
Arjen Amelink, Henricus J. C.
M. Sterenborg, Martin P. L. Bard, and Sjaak A. Burgers, "In vivo measurement of the local optical properties
of tissue by use of differential path-length spectroscopy," Opt. Lett. 29, 1087-1089 (2004)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-29-10-1087
You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
Related Journal Articles 
- Polarized wavelength-dependent measurements of turbid media (OE)
- Particle size analysis of turbid media with a single optical fiber in contact with the medium to deliver and detect white light (AO)
- Characterizing Mammalian Cells and Cell Phantoms by Polarized Backscattering Fiber-Optic Measurements (AO)
- Single-Scattering Spectroscopy for the Endoscopic Analysis of Particle Size in Superficial Layers of Turbid Media (AO)
- Measurement of the Local Optical Properties of Turbid Media by Differential Path-Length Spectroscopy (AO)
Related Conference Papers
- Fractal Mechanisms of Light Scattering in Biological Tissue and Cells
- Scattering properties of biological cells
- Using few-mode fiber to improve the signal-to-noise ratio of DCS flow-oximeter measurements
- Diffuse optical detecting hemodynamic responses during fatiguing exercise in women with fibromyalgia
- Comparison of diffuse optical spectroscopies and electroencephalogram for cerebral monitoring during carotid endarterectomy
« Previous Article | Next Article »
OSA is a member of 