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Optics Letters

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  • Vol. 29, Iss. 17 — Sep. 1, 2004
  • pp: 2043–2045

Absorption and scattering imaging of tissue with steady-state second-differential spectral-analysis tomography

Heng Xu, Brian W. Pogue, Hamid Dehghani, Keith D. Paulsen, Roger Springett, and Jeff F. Dunn  »View Author Affiliations


Optics Letters, Vol. 29, Issue 17, pp. 2043-2045 (2004)
http://dx.doi.org/10.1364/OL.29.002043


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Abstract

A novel approach to reconstructing both the absorption and the scattering properties of a turbid medium simultaneously from steady-state broadband spectral measurements is presented that utilizes second-differential fitting to the water spectrum to estimate the optical path length in tissue. Theoretical and experimental evidence is provided to demonstrate the robust accuracy of the spectroscopy approach and reconstructed absorption images. The steady-state broadband CCD system has the potential to provide accurate chromophore imaging without the technological complexity of time- or frequency-domain systems.

© 2004 Optical Society of America

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(170.6960) Medical optics and biotechnology : Tomography

Citation
Heng Xu, Brian W. Pogue, Hamid Dehghani, Keith D. Paulsen, Roger Springett, and Jeff F. Dunn, "Absorption and scattering imaging of tissue with steady-state second-differential spectral-analysis tomography," Opt. Lett. 29, 2043-2045 (2004)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-29-17-2043


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References

  1. S. R. Arridge and W. R. B. Lionheart, Opt. Lett. 23, 882 (1998).
  2. A. Corlu, T. Durduran, R. Choe, M. Schweiger, E. M. C. Hillman, S. R. Arridge, and A. G. Yodh, Opt. Lett. 28, 2339 (2003).
  3. A. Li, Q. Zhang, J. P. Culver, E. L. Miller, and D. A. Boas, Opt. Lett. 29, 256 (2004).
  4. H. Jiang, K. D. Paulsen, U. L. Osterberg, B. W. Pogue, and M. S. Patterson, J. Opt. Soc. Am. A 13, 253 (1996).
  5. S. R. Arridge, M. Cope, and D. T. Delpy, Phys. Med. Biol. 37, 1531 (1992).
  6. S. J. Matcher, M. Cope, and D. T. Delpy, Phys. Med. Biol. 39, 177 (1994).
  7. H. Xu, B. W. Pogue, H. Dehghani, R. Springett, K. D. Paulsen, and J. F. Dunn, Proc. SPIE 4955, 16 (2003).
  8. R. F. Reinoso, B. A. Telfer, and M. Rowland, J. Pharmacol. Toxicol. Methods 38, 87 (1997).
  9. B. L. Horecker, J. Biol. Chem. 148, 173 (1943).
  10. V. Hollis, “Noninvasive monitoring of brain-tissue temperature by near-infrared spectroscopy,” Ph.D. dissertation (University College, London, 2002).
  11. H. J. van Staveren, C. J. M. Moses, J. van Marle, S. A. Prahl, and M. J. C. van Gemert, Appl. Opt. 30, 4507 (1991).

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