Interstitial Doppler optical coherence tomography
Optics Letters, Vol. 30, Issue 14, pp. 1791-1793 (2005)
http://dx.doi.org/10.1364/OL.30.001791
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Abstract
Doppler optical coherence tomography (OCT) can image tissue structure and blood flow at micrometer-scale resolution but has limited imaging depth. We report a novel, linear-scanning, needle-based Doppler OCT system using angle-polished gradient-index or ball-lensed fibers. A prototype system with a 19-guage (diameter of ∼0.9 mm) echogenic needle is constructed and demonstrates in vivo imaging of bidirectional blood flow in rat leg and abdominal cavity. To our knowledge, this is the first demonstration of Doppler OCT through a needle probe in interstitial applications to visualize deeply situated microcirculation.
© 2005 Optical Society of America
OCIS Codes
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.6930) Medical optics and biotechnology : Tissue
Citation
Victor X. D. Yang, You X. Mao, Nigel Munce, Beau Standish, Walter Kucharczyk, Norman E. Marcon, Brian C. Wilson, and I. Alex Vitkin, "Interstitial Doppler optical coherence tomography," Opt. Lett. 30, 1791-1793 (2005)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-30-14-1791
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