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Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Anthony J. Campillo
  • Vol. 31, Iss. 16 — Aug. 15, 2006
  • pp: 2453–2455

In vivo three-dimensional photoacoustic tomography of a whole mouse head

Kwang Hyun Song, George Stoica, and Lihong V. Wang  »View Author Affiliations


Optics Letters, Vol. 31, Issue 16, pp. 2453-2455 (2006)
http://dx.doi.org/10.1364/OL.31.002453


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Abstract

An in vivo photoacoustic imaging system was designed and implemented to image the entire small animal head. A special scanning gantry was designed to enable in vivo imaging in coronal cross sections with high contrast and good spatial resolution for the first time to our knowledge. By use of a 2.25 MHz ultrasonic transducer with a 6 mm diameter active element, an in-plane radial resolution of 312 μ m was achieved. Deeply seated arterial and venous vessels in the head measuring up to 1.7 cm in diameter were simultaneously imaged in vivo with 804 nm wavelength laser excitation of photoacoustic waves.

© 2006 Optical Society of America

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5120) Medical optics and biotechnology : Photoacoustic imaging

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: April 4, 2006
Revised Manuscript: May 15, 2006
Manuscript Accepted: May 17, 2006
Published: July 25, 2006

Virtual Issues
Vol. 1, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Kwang Hyun Song, George Stoica, and Lihong V. Wang, "In vivo three-dimensional photoacoustic tomography of a whole mouse head," Opt. Lett. 31, 2453-2455 (2006)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-31-16-2453

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