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Optics Letters

Optics Letters


  • Editor: Anthony J. Campillo
  • Vol. 31, Iss. 16 — Aug. 15, 2006
  • pp: 2495–2497

Highly sensitive single-beam heterodyne coherent anti-Stokes Raman scattering

Bernhard von Vacano, Tiago Buckup, and Marcus Motzkus  »View Author Affiliations

Optics Letters, Vol. 31, Issue 16, pp. 2495-2497 (2006)

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Single-beam coherent anti-Stokes Raman-scattering (CARS) microspectroscopy achieves a complete CARS scheme with a femtosecond laser. Here, we introduce heterodyne detection in a simple experimental extension: the optical fields driving the CARS process and the local oscillator used for heterodyning are derived from a single beam of ultrashort laser pulses by pulse shaping. The heterodyne signal is amplified by more than 3 orders of magnitude and is linearly dependent on the concentration of Raman scatterers. This dramatically increases the sensitivity of chemically selective detection at microscopic resolution while maintaining the simplicity of the single-beam setup.

© 2006 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(180.0180) Microscopy : Microscopy
(300.6230) Spectroscopy : Spectroscopy, coherent anti-Stokes Raman scattering
(320.5540) Ultrafast optics : Pulse shaping

ToC Category:

Original Manuscript: May 19, 2006
Revised Manuscript: June 7, 2006
Manuscript Accepted: June 8, 2006
Published: July 25, 2006

Virtual Issues
Vol. 1, Iss. 9 Virtual Journal for Biomedical Optics

Bernhard von Vacano, Tiago Buckup, and Marcus Motzkus, "Highly sensitive single-beam heterodyne coherent anti-Stokes Raman scattering," Opt. Lett. 31, 2495-2497 (2006)

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