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Optics Letters

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  • Editor: Anthony J. Campillo
  • Vol. 31, Iss. 6 — Mar. 15, 2006
  • pp: 769–771

Comparison of noncontact and fiber-based fluorescence-mediated tomography

Ralf B. Schulz, Jörg Peter, Wolfhard Semmler, Cosimo D’Andrea, Gianluca Valentini, and Rinaldo Cubeddu  »View Author Affiliations


Optics Letters, Vol. 31, Issue 6, pp. 769-771 (2006)
http://dx.doi.org/10.1364/OL.31.000769


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Abstract

We present a comparative experimental phantom study of fiber-based and noncontact fluorescence tomography with respect to quantitation and localization of reconstructed fluorescent inclusions in turbid media such as tissue. Noncontact acquisition is usually considered potentially superior to fiber-based techniques because of the availability of a large number of detector readouts through a CCD. Our results indicate, however, that noncontact acquisition itself might improve the quality of reconstructions significantly, even without increasing the number of detectors and thus keeping the inverse problem moderately complex.

© 2006 Optical Society of America

OCIS Codes
(120.1880) Instrumentation, measurement, and metrology : Detection
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.6960) Medical optics and biotechnology : Tomography
(170.7050) Medical optics and biotechnology : Turbid media
(260.2510) Physical optics : Fluorescence

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: September 23, 2005
Revised Manuscript: December 1, 2005
Manuscript Accepted: December 4, 2005

Virtual Issues
Vol. 1, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Ralf B. Schulz, Jörg Peter, Wolfhard Semmler, Cosimo D'Andrea, Gianluca Valentini, and Rinaldo Cubeddu, "Comparison of noncontact and fiber-based fluorescence-mediated tomography," Opt. Lett. 31, 769-771 (2006)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-31-6-769


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References

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