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Optics Letters

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  • Editor: Anthony J. Campillo
  • Vol. 32, Iss. 3 — Feb. 1, 2007
  • pp: 253–255

Wide dynamic range detection of bidirectional flow in Doppler optical coherence tomography using a two-dimensional Kasai estimator

Darren Morofke, Michael C. Kolios, I. Alex Vitkin, and Victor X.D. Yang  »View Author Affiliations


Optics Letters, Vol. 32, Issue 3, pp. 253-255 (2007)
http://dx.doi.org/10.1364/OL.32.000253


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Abstract

We demonstrate extended axial flow velocity detection range in a time-domain Doppler optical coherence tomography (DOCT) system using a modified Kasai velocity estimator with computations in both the axial and transverse directions. For a DOCT system with an 8 kHz rapid-scanning optical delay line, bidirectional flow experiments showed a maximum detectable speed of > 56 cm s using the axial Kasai estimator without the occurrence of aliasing, while the transverse Kasai estimator preserved the 7 μ m s minimum detectable velocity to slow flow. By using a combination of transverse Kasai and axial Kasai estimators, the velocity detection dynamic range was over 100 dB . Through a fiber-optic endoscopic catheter, in vivoM-mode transesophageal imaging of the pulsatile blood flow in rat aorta was demonstrated, for what is for the first time to our knowledge, with measured peak systolic blood flow velocity of > 1 m s , while maintaining good sensitivity to detect aortic wall motion at < 2 mm s , using this 2D Kasai technique.

© 2007 Optical Society of America

OCIS Codes
(100.2000) Image processing : Digital image processing
(110.4500) Imaging systems : Optical coherence tomography
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: August 30, 2006
Manuscript Accepted: October 16, 2006
Published: January 12, 2007

Virtual Issues
Vol. 2, Iss. 3 Virtual Journal for Biomedical Optics

Citation
Darren Morofke, Michael C. Kolios, I. Alex Vitkin, and Victor X. D. Yang, "Wide dynamic range detection of bidirectional flow in Doppler optical coherence tomography using a two-dimensional Kasai estimator," Opt. Lett. 32, 253-255 (2007)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-32-3-253


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