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Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Alan E. Willner
  • Vol. 33, Iss. 21 — Nov. 1, 2008
  • pp: 2479–2481

High-speed, high-resolution Fourier-domain optical coherence tomography system for retinal imaging in the 1060 nm wavelength region

Prabakar Puvanathasan, Peter Forbes, Zhao Ren, Doug Malchow, Shelley Boyd, and Kostadinka Bizheva  »View Author Affiliations


Optics Letters, Vol. 33, Issue 21, pp. 2479-2481 (2008)
http://dx.doi.org/10.1364/OL.33.002479


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Abstract

A high-speed ( 47,000 A - scans s ) , ultrahigh axial resolution Fourier domain optical coherence tomography (OCT) system for retinal imaging at 1060 nm , based on a 1024   pixel linear array, 47 kHz readout rate InGaAs camera is presented. When interfaced with a custom superluminescent diode ( λ c = 1020 nm , Δ λ = 108 nm , P out = 9 mW ), the system provides 3.3 μ m axial OCT resolution at the surface of biological tissue, 4.5 μ m in vivo in rat retina, 5.7 μ m in vivo in human retina, and 110 dB sensitivity for 870 μ W incident power and 21 μ s integration time. Retinal tomograms acquired in vivo from a human volunteer and a rat animal model show clear visualization of all intraretinal layer and increased penetration into the choroid.

© 2008 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: March 24, 2008
Revised Manuscript: June 10, 2008
Manuscript Accepted: September 4, 2008
Published: October 23, 2008

Virtual Issues
Vol. 4, Iss. 1 Virtual Journal for Biomedical Optics

Citation
Prabakar Puvanathasan, Peter Forbes, Zhao Ren, Doug Malchow, Shelley Boyd, and Kostadinka Bizheva, "High-speed, high-resolution Fourier-domain optical coherence tomography system for retinal imaging in the 1060 nm wavelength region," Opt. Lett. 33, 2479-2481 (2008)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-33-21-2479


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