Simultaneous multiwavelength laminar optical tomography
Optics Letters, Vol. 33, Issue 22, pp. 2710-2712 doi:10.1364/OL.33.002710
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- OCIS Codes:
- (170.0110) Medical optics and biotechnology : Imaging systems
- (110.4234) Imaging systems : Multispectral and hyperspectral imaging
Imaging Systems
Citation
Sean A. Burgess, Matthew B. Bouchard, Baohong Yuan, and Elizabeth M. C. Hillman, "Simultaneous multiwavelength laminar optical tomography," Opt. Lett. 33, 2710-2712 (2008)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-33-22-2710
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- Vol. 4, Iss. 1 Virtual Journal for Biomedical Optics
Abstract
Spatially resolved reflectance measurements can be used to characterize the depth-resolved optical properties of superficial tissues. However, until now, rapid acquisition of multiwavelength data has been hindered by multiplexing problems. We report on a novel multiwavelength laminar optical tomography system capable of acquiring data from multiple source-detector separations at three wavelengths simultaneously. Such data can allow in vivo depth-resolved spectroscopic imaging of absorbers, such as oxy- and deoxyhemoglobin, or of multiple fluorophores, that is unaffected by motion artifacts at frame rates exceeding 100 Hz. The system design and phantom validation studies are presented.
© 2008 Optical Society of America
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History
Original Manuscript: July 29, 2008
Manuscript Accepted: September 11, 2008
Published: November 14, 2008
References
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Author Affiliations
Columbia University
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