We report experimental evidence and correction of defocus in full-field optical coherence tomography of biological samples owing to mismatch of the refractive index of biological tissues and water. Via a metric based on the image quality, we demonstrate that we are able to compensate this index-induced defocus and to recover a sharp image in depth.
© 2009 Optical Society of America
Original Manuscript: January 7, 2009
Revised Manuscript: April 14, 2009
Manuscript Accepted: April 14, 2009
Published: May 13, 2009
Vol. 4, Iss. 7 Virtual Journal for Biomedical Optics
S. Labiau, G. David, S. Gigan, and A. C. Boccara, "Defocus test and defocus correction in full-field optical coherence tomography," Opt. Lett. 34, 1576-1578 (2009)