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Laser-scanning optical-resolution photoacoustic microscopy

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Abstract

We have developed a laser-scanning optical-resolution photoacoustic microscopy method that can potentially fuse with existing optical microscopic imaging modalities. To acquire an image, the ultrasonic transducer is kept stationary during data acquisition, and only the laser light is raster scanned by an xy galvanometer scanner. A lateral resolution of 7.8μm and a circular field of view with a diameter of 6mm were achieved in an optically clear medium. Using a laser system working at a pulse repetition rate of 1024Hz, the data acquisition time for an image consisting of 256×256  pixels was less than 2 min.

© 2009 Optical Society of America

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