Abstract

The combination of intravascular ultrasound and intravascular photoacoustic imaging has been proposed for improving the diagnosis of arterial diseases. We describe a novel scan-head design for implementing such multimodality imaging. The proposed device has the potential to achieve a sufficiently small size for clinical intravascular applications. The design aims for efficient image data acquisition for facilitating real-time three-dimensional imaging and reducing the required laser pulse repetition frequency. The integrated scan head consists of a single- element, ring-shaped transducer for sideward ultrasound transmission, a multimode fiber with a cone-shaped mirror for optical illumination, and a single polymer microring with mechanical scanning. The phantom imaging and some experimental results are presented. A microring array can be realized in the future to achieve high- frame-rate intravascular multimodality imaging.

© 2010 Optical Society of America

Intravascular photoacoustic imaging of human coronary atherosclerosis

Krista Jansen, Antonius F. W. van der Steen, Heleen M. M. van Beusekom, J. Wolter Oosterhuis, and Gijs van Soest
Opt. Lett. 36(5) 597-599 (2011)

Detection of lipid in atherosclerotic vessels using ultrasound-guided spectroscopic intravascular photoacoustic imaging

Bo Wang, Jimmy L. Su, James Amirian, Silvio H. Litovsky, Richard Smalling, and Stanislav Emelianov
Opt. Express 18(5) 4889-4897 (2010)

Multi-spectral intravascular photoacoustic/ultrasound/optical coherence tomography tri-modality system with a fully-integrated 0.9-mm full field-of-view catheter for plaque vulnerability imaging

Ji Leng, Jinke Zhang, Chenguang Li, Chengyou Shu, Boquan Wang, Riqiang Lin, Yanmei Liang, Keqiang Wang, Li Shen, Kwok-ho Lam, Zhihua Xie, Xiaojing Gong, Junbo Ge, and Liang Song
Biomed. Opt. Express 12(4) 1934-1946 (2021)

Intravascular photoacoustic imaging of lipid in atherosclerotic plaques in the presence of luminal blood

Bo Wang, Andrei Karpiouk, Doug Yeager, James Amirian, Silvio Litovsky, Richard Smalling, and Stanislav Emelianov
Opt. Lett. 37(7) 1244-1246 (2012)

Combined frequency domain photoacoustic and ultrasound imaging for intravascular applications

Robin F. Castelino, Michael Hynes, Chelsea E. Munding, Sergey Telenkov, and F. Stuart Foster
Biomed. Opt. Express 7(11) 4441-4449 (2016)