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Optics Letters

Optics Letters


  • Editor: Alan E. Willner
  • Vol. 35, Iss. 3 — Feb. 1, 2010
  • pp: 360–362

Measuring morphological features using light-scattering spectroscopy and Fourier-domain low-coherence interferometry

Francisco E. Robles and Adam Wax  »View Author Affiliations

Optics Letters, Vol. 35, Issue 3, pp. 360-362 (2010)

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We present measurements of morphological features in a thick turbid sample using light-scattering spectroscopy (LSS) and Fourier-domain low-coherence interferometry (fLCI) by processing with the dual-window (DW) method. A parallel frequency domain optical coherence tomography (OCT) system with a white-light source is used to image a two-layer phantom containing polystyrene beads of diameters 4.00 and 6.98 μ m on the top and bottom layers, respectively. The DW method decomposes each OCT A-scan into a time–frequency distribution with simultaneously high spectral and spatial resolution. The spectral information from localized regions in the sample is used to determine scatterer structure. The results show that the two scatterer populations can be differentiated using LSS and fLCI.

© 2010 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(290.1350) Scattering : Backscattering
(300.0300) Spectroscopy : Spectroscopy

ToC Category:

Original Manuscript: September 25, 2009
Revised Manuscript: November 24, 2009
Manuscript Accepted: December 3, 2009
Published: January 26, 2010

Virtual Issues
Vol. 5, Iss. 4 Virtual Journal for Biomedical Optics

Francisco E. Robles and Adam Wax, "Measuring morphological features using light-scattering spectroscopy and Fourier-domain low-coherence interferometry," Opt. Lett. 35, 360-362 (2010)

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  1. L. T. Perelman, V. Backman, M. Wallace, G. Zonios, R. Manoharan, A. Nusrat, S. Shields, M. Seiler, C. Lima, T. Hamano, I. Itzkan, J. Van Dam, J. M. Crawford, and M. S. Feld, Phys. Rev. Lett. 80, 627 (1998). [CrossRef]
  2. R. N. Graf and A. Wax, Opt. Express 13, 4693 (2005). [CrossRef]
  3. V. Kumar, A. K. Abbas, and N. Fausto, Robbin and Cotran Pathologic Basis of Disease (Elsevier/Saunders, 2005).
  4. U. Morganer, W. Drexler, F. X. Kärtner, X. D. Li, C. Pitris, E. P. Ippen, and J. G. Fujimoto, Opt. Lett. 25, 111 (2000). [CrossRef]
  5. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991). [CrossRef] [PubMed]
  6. F. Robles, R. N. Graf, and A. Wax, Opt. Express 17, 6799 (2009). [CrossRef] [PubMed]
  7. R. N. Graf, W. J. Brown, and A. Wax, Opt. Lett. 33, 1285 (2008). [CrossRef] [PubMed]
  8. Y. Zhu, N. Terry, and A. Wax, Opt. Lett. 34, 3196 (2009). [CrossRef] [PubMed]
  9. H. C. Van de Hulst, Light Scattering by Small Particles (Dover, 1957), pp. 173-199.
  10. J. Yi, J. Gong, and X. Li, Opt. Express 17, 13157 (2009). [CrossRef] [PubMed]
  11. R. N. Graf, F. E. Robles, and A. Wax, J. Biomed. Opt. 14, 064030 (2009). [CrossRef]

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