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Optics Letters

Optics Letters


  • Vol. 36, Iss. 16 — Aug. 15, 2011
  • pp: 3284–3286

Potential mapping of optical tweezers

Tahmineh Godazgar, Rouzbeh Shokri, and S. Nader S. Reihani  »View Author Affiliations

Optics Letters, Vol. 36, Issue 16, pp. 3284-3286 (2011)

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Optical tweezers are very often used for measurement of piconewton range forces. Depending on the displacement of the trapped bead, the trap may become stiffer which causes considerable underestimation of the measured force. We have shown, both by theory and experiment, that such a stiffening occurs for beads larger than 0.5 μm in radius. For the first time, we have shown that the displacement at which the stiffening starts is size dependent and that the stiffening starts at higher forces for larger beads. We have shown that for the applications, which simultaneous force measurement and position sensing are on demand (such as biopolymer stretching), mid-range sized ( 1.5 μm in radius) beads could be the best choice.

© 2011 Optical Society of America

OCIS Codes
(140.7010) Lasers and laser optics : Laser trapping
(170.4520) Medical optics and biotechnology : Optical confinement and manipulation
(350.4855) Other areas of optics : Optical tweezers or optical manipulation

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: April 8, 2011
Revised Manuscript: July 19, 2011
Manuscript Accepted: July 28, 2011
Published: August 15, 2011

Virtual Issues
Vol. 6, Iss. 9 Virtual Journal for Biomedical Optics

Tahmineh Godazgar, Rouzbeh Shokri, and S. Nader S. Reihani, "Potential mapping of optical tweezers," Opt. Lett. 36, 3284-3286 (2011)

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