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Optics Letters

Optics Letters


  • Editor: Alan E. Willner
  • Vol. 37, Iss. 19 — Oct. 1, 2012
  • pp: 3969–3971

Multiple resonance fiber-optic sensor with time division multiplexing for multianalyte detection

Hsing-Ying Lin, Chen-Han Huang, Chia-Chi Huang, Yu-Chia Liu, and Lai-Kwan Chau  »View Author Affiliations

Optics Letters, Vol. 37, Issue 19, pp. 3969-3971 (2012)

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A proof-of-concept multiwindow fiber-optic sensor utilizing multiple particle plasmon resonance (PPR) of silver nanoparticles and gold nanorods separately on two unclad portions of the fiber for multianalyte detection is demonstrated. The detection is based on intensity interrogation of multiple wavelengths by a single detector. Time division multiplexing is employed to modulate the illumination of dual-wavelength LEDs to induce PPRs for simultaneous real-time and label-free monitoring of two types of biomolecular interactions. Preliminary results reveal that a refractive index resolution of 9×106RIU is achieved. Moreover, the measured intensities of two windows independently respond to their respective binding events. The potential of the sensor architecture with multiple sensing windows for cascaded, higher throughput, and multianalyte biochemical detection can be expected.

© 2012 Optical Society of America

OCIS Codes
(060.2280) Fiber optics and optical communications : Fiber design and fabrication
(060.2370) Fiber optics and optical communications : Fiber optics sensors
(060.4230) Fiber optics and optical communications : Multiplexing
(240.6680) Optics at surfaces : Surface plasmons

ToC Category:
Fiber Optics and Optical Communications

Original Manuscript: May 28, 2012
Revised Manuscript: July 29, 2012
Manuscript Accepted: August 20, 2012
Published: September 19, 2012

Hsing-Ying Lin, Chen-Han Huang, Chia-Chi Huang, Yu-Chia Liu, and Lai-Kwan Chau, "Multiple resonance fiber-optic sensor with time division multiplexing for multianalyte detection," Opt. Lett. 37, 3969-3971 (2012)

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