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Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Alan E. Willner
  • Vol. 37, Iss. 19 — Oct. 1, 2012
  • pp: 4080–4082

Model-based optoacoustic imaging using focused detector scanning

Miguel Ángel Araque Caballero, Amir Rosenthal, Jérôme Gateau, Daniel Razansky, and Vasilis Ntziachristos  »View Author Affiliations


Optics Letters, Vol. 37, Issue 19, pp. 4080-4082 (2012)
http://dx.doi.org/10.1364/OL.37.004080


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Abstract

Optoacoustic (photoacoustic) mesoscopic and microscopic imaging is often implemented by linearly scanning a spherically focused ultrasound transducer. In this case, the resolution and sensitivity along the scan direction are limited by diffraction and therefore degrade rapidly for imaging depths away from the focal point. Partial restoration of the lost resolution can be achieved by using data-processing techniques, such as the virtual detector delay-and-sum method. However, these techniques are based on an approximate description of the detector properties, which limits the improvement in image quality they achieve. Herein we propose a reconstruction method based on an exact model of the optoacoustic generation and propagation that incorporates the spatial response of the sensor. The proposed method shows superior imaging performance over previously considered techniques.

© 2012 Optical Society of America

OCIS Codes
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5120) Medical optics and biotechnology : Photoacoustic imaging

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: July 17, 2012
Manuscript Accepted: August 11, 2012
Published: September 26, 2012

Citation
Miguel Ángel Araque Caballero, Amir Rosenthal, Jérôme Gateau, Daniel Razansky, and Vasilis Ntziachristos, "Model-based optoacoustic imaging using focused detector scanning," Opt. Lett. 37, 4080-4082 (2012)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-37-19-4080


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References

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  11. 9 days old, shaved CD1 (r) specimen, Charles River Laboratories, Research Models and Services, Germany GmbH. The mouse was euthanized with an intraperitoneal overdose of ketamine/Xylacin.

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