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Optics Letters


  • Editor: Alan E. Willner
  • Vol. 38, Iss. 14 — Jul. 15, 2013
  • pp: 2629–2631

Imaging of the interaction of low-frequency electric fields with biological tissues by optical coherence tomography

Adrian F. Peña, Jack Devine, Alexander Doronin, and Igor Meglinski  »View Author Affiliations

Optics Letters, Vol. 38, Issue 14, pp. 2629-2631 (2013)

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Low-frequency electric fields propagating in ex vivo biological tissues have been observed by using double-correlation optical coherence tomography (OCT). An adaptive Wiener filtering approach has been used to remove background noise, and a Fourier domain correlation algorithm has been applied to the sequence of OCT images. The results present the first direct observation (to our knowledge) of the scope of the electric field influencing biological tissues with OCT. The results show that variation in voltage and frequency of the applied electric field relates exponentially to the magnitude of its influence on biological tissue. The magnitude of influence is about twice more for fresh tissue samples in comparison to nonfresh ones. The obtained results suggest that OCT can be used for observation and quantitative evaluation of the electrokinetic changes in biological tissues under different physiological conditions, functional electrical stimulation, and food quality control.

© 2013 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging
(170.6935) Medical optics and biotechnology : Tissue characterization

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: April 11, 2013
Revised Manuscript: June 7, 2013
Manuscript Accepted: June 14, 2013
Published: July 15, 2013

Virtual Issues
Vol. 8, Iss. 8 Virtual Journal for Biomedical Optics

Adrian F. Peña, Jack Devine, Alexander Doronin, and Igor Meglinski, "Imaging of the interaction of low-frequency electric fields with biological tissues by optical coherence tomography," Opt. Lett. 38, 2629-2631 (2013)

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