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Optics Letters

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  • Editor: Alan E. Willner
  • Vol. 38, Iss. 18 — Sep. 15, 2013
  • pp: 3690–3692

Dual-wavelength laser speckle imaging to simultaneously access blood flow, blood volume, and oxygenation using a color CCD camera

Jia Wang, Yaru Wang, Bing Li, Danqi Feng, Jinling Lu, Qingming Luo, and Pengcheng Li  »View Author Affiliations


Optics Letters, Vol. 38, Issue 18, pp. 3690-3692 (2013)
http://dx.doi.org/10.1364/OL.38.003690


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Abstract

We developed a dual-wavelength laser speckle imaging system using a single industrial-grade color CCD camera with Bayer filters to simultaneously image changes in blood flow, blood volume, and oxygenation. One frame of a color image recorded with dual-wavelength laser illumination provides not only the intensity fluctuation of the speckle pattern, but also the dual-wavelength optical reflectance signal. The method was validated using a tissue phantom and cuff ischemia experiments in the human arm. This system achieves complete time synchronization, unlike conventional time-sharing systems. Compared with a multicamera system, it also avoids the problem of image registration and can be less expensive.

© 2013 Optical Society of America

OCIS Codes
(110.6150) Imaging systems : Speckle imaging
(170.0110) Medical optics and biotechnology : Imaging systems
(170.3880) Medical optics and biotechnology : Medical and biological imaging

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: December 19, 2012
Revised Manuscript: July 6, 2013
Manuscript Accepted: August 7, 2013
Published: September 13, 2013

Virtual Issues
Vol. 8, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Jia Wang, Yaru Wang, Bing Li, Danqi Feng, Jinling Lu, Qingming Luo, and Pengcheng Li, "Dual-wavelength laser speckle imaging to simultaneously access blood flow, blood volume, and oxygenation using a color CCD camera," Opt. Lett. 38, 3690-3692 (2013)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-38-18-3690


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