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Optics Letters

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  • Editor: Alan E. Willner
  • Vol. 38, Iss. 9 — May. 1, 2013
  • pp: 1512–1514

Noninvasive imaging of pulsatile movements of the optic nerve head in normal human subjects using phase-sensitive spectral domain optical coherence tomography

Lin An, Jennifer Chao, Murray Johnstone, and Ruikang K. Wang  »View Author Affiliations


Optics Letters, Vol. 38, Issue 9, pp. 1512-1514 (2013)
http://dx.doi.org/10.1364/OL.38.001512


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Abstract

We report use of high-speed spectral domain optical coherence tomography to noninvasively image pulsatile axial movement of the optic nerve head (ONH) in normal human subjects. Time-lapse B-scan mode is used to image the ONH at 500 frames per second. Capture of phase differences between adjacent B-scans permits extraction of axial ONH movement. We find the ONH experiences continuous oscillatory axial motion that is strongly correlated with simultaneously measured pulsatile blood flow in the central retinal artery.

© 2013 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: December 17, 2012
Revised Manuscript: March 29, 2013
Manuscript Accepted: March 29, 2013
Published: April 26, 2013

Virtual Issues
Vol. 8, Iss. 6 Virtual Journal for Biomedical Optics

Citation
Lin An, Jennifer Chao, Murray Johnstone, and Ruikang K. Wang, "Noninvasive imaging of pulsatile movements of the optic nerve head in normal human subjects using phase-sensitive spectral domain optical coherence tomography," Opt. Lett. 38, 1512-1514 (2013)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-38-9-1512


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