OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Alan E. Willner
  • Vol. 38, Iss. 9 — May. 1, 2013
  • pp: 1515–1517

Flexible endoscope for continuous in vivo multispectral fluorescence lifetime imaging

Shuna Cheng, J. Jesus Rico-Jimenez, Joey Jabbour, Bilal Malik, Kristen C. Maitland, John Wright, Yi-Shing Lisa Cheng, and Javier A. Jo  »View Author Affiliations


Optics Letters, Vol. 38, Issue 9, pp. 1515-1517 (2013)
http://dx.doi.org/10.1364/OL.38.001515


View Full Text Article

Enhanced HTML    Acrobat PDF (312 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

Fluorescence lifetime imaging (FLIM) offers a noninvasive approach for characterizing the biochemical composition of biological tissue. There has been an increasing interest in the application of multispectral FLIM for medical diagnosis. Central to the clinical translation of FLIM technology is the development of compact and high-speed endoscopy systems. Unfortunately, the predominant multispectral FLIM approaches suffer from limitations that impede the development of endoscopy systems that are suitable for in vivo tissue imaging. We present a compact wide-field time-gated FLIM flexible endoscope capable of continuous lifetime imaging of up to three fluorescence emission bands simultaneously. This endoscope design will facilitate the evaluation of FLIM for in vivo applications.

© 2013 Optical Society of America

OCIS Codes
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.2520) Medical optics and biotechnology : Fluorescence microscopy
(170.6920) Medical optics and biotechnology : Time-resolved imaging

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: February 22, 2013
Revised Manuscript: March 26, 2013
Manuscript Accepted: March 26, 2013
Published: April 26, 2013

Virtual Issues
Vol. 8, Iss. 6 Virtual Journal for Biomedical Optics

Citation
Shuna Cheng, J. Jesus Rico-Jimenez, Joey Jabbour, Bilal Malik, Kristen C. Maitland, John Wright, Yi-Shing Lisa Cheng, and Javier A. Jo, "Flexible endoscope for continuous in vivo multispectral fluorescence lifetime imaging," Opt. Lett. 38, 1515-1517 (2013)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-38-9-1515

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

Supplementary Material


» Media 1: AVI (405 KB)     
» Media 2: AVI (571 KB)     

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited