Optical low-coherence reflectometry is applied for the first time to our knowledge to investigate diffusive biological tissues with a single-mode fiber probe. Samples of fresh arteries are studied, using the backscattered light from the tissue. The probed volume in the vicinity of the fiber tip is estimated to be below 6.7 × 10−10 cm3. This noninvasive method allows one to determine optical parameters, such as the index of refraction and the transmission properties, and the tissue thickness.
© 1992 Optical Society of America
Original Manuscript: August 27, 1991
Published: January 1, 1992
X. Clivaz, R. P. Novàk, H. H. Gilgen, F. Marquis-Weible, and R. P. Salathé, "High-resolution reflectometry in biological tissues," Opt. Lett. 17, 4-6 (1992)