The development of techniques for high-speed image acquisition in optical coherence tomography (OCT) systems is essential for suppressing motion artifacts when one is imaging living systems. We describe a new OCT system for performing micrometer-scale, cross-sectional optical imaging at four images/s. To achieve OCT image-acquisition times of less than 1 s, we use a piezoelectric fiber stretcher to vary the reference arm delay. A Kerr-lens mode-locked chromium-doped forsterite laser is employed as the low-coherence source for the highspeed OCT system. Dynamic, motion-artifact-free in vivo imaging of a beating Xenopus laevis (African frog) heart is demonstrated.
© 1996 Optical Society of America
Original Manuscript: March 13, 1996
Published: September 1, 1996
G. J. Tearney, E. A. Swanson, J. G. Fujimoto, B. E. Bouma, S. A. Boppart, and B. Golubovic, "Rapid acquisition of in vivo biological images by use of optical coherence tomography," Opt. Lett. 21, 1408-1410 (1996)