OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Vol. 21, Iss. 18 — Sep. 15, 1996
  • pp: 1519–1521

Determination of absorption coefficients in highly scattering media from changes in attenuation and phase

Matthias Kohl, Russell Watson, and Mark Cope  »View Author Affiliations


Optics Letters, Vol. 21, Issue 18, pp. 1519-1521 (1996)
http://dx.doi.org/10.1364/OL.21.001519


View Full Text Article

Enhanced HTML    Acrobat PDF (286 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

The accurate, quantitative analysis of absorption and scattering properties in tissue is a central problem in biochemical optics, in particular for the determination of hemoglobin and oxyhemoglobin concentrations. Because of light scattering, the absolute concentrations of these chromophores (i.e., the absorption coefficient) cannot easily be inferred. A new method for the estimation of the absorption coefficients in scattering media, based on measurements obtained from an intensity-modulated optical spectrometer, is proposed. The ratios of the changes in attenuation and phase that are induced by changes in the absorption coefficient give a good approximation of the absorption coefficient.

© 1996 Optical Society of America

History
Original Manuscript: April 4, 1996
Published: September 15, 1996

Citation
Matthias Kohl, Russell Watson, and Mark Cope, "Determination of absorption coefficients in highly scattering media from changes in attenuation and phase," Opt. Lett. 21, 1519-1521 (1996)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-21-18-1519


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. S. Fantini, M. A. Franceschini, J. Fishkin, B. Barbieri, E. Gratton, Appl. Opt. 33, 5204 (1994). [CrossRef] [PubMed]
  2. J. B. Fishkin, P. T. So, A. E. Cerussi, S. Fantini, M. A. Franceschini, E. Gratton, Appl. Opt. 34, 1143 (1995). [CrossRef] [PubMed]
  3. W. Pogue, M. S. Patterson, Phys. Med. Biol. 39, 1157 (1994). [CrossRef] [PubMed]
  4. A. Duncan, T. L. Whitlock, M. Cope, D. T. Delpy, Proc. SPIE 1888, 248 (1993). [CrossRef]
  5. J. Tromberg, L. O. Svaasand, T.-T. Tsay, R. Haskell, Appl. Opt. 32, 607 (1993). [CrossRef] [PubMed]
  6. S. J. Madsen, E. R. Anderson, R. C. Haskell, B. J. Tromberg, Opt. Lett. 19, 1934 (1994). [CrossRef] [PubMed]
  7. J. Farrell, B. C. Wilson, M. S. Patterson, Phys. Med. Biol. 37, 2281 (1992). [CrossRef] [PubMed]
  8. M. S. Patterson, B. Chance, B. Wilson, Appl. Opt. 28, 2331 (1989). [CrossRef] [PubMed]
  9. S. Arridge, M. Cope, D. T. Delpy, Phys. Med. Biol. 37, 1531 (1992). [CrossRef] [PubMed]
  10. F. Bohren, D. R. Huffman, Absorption and Scattering of Light by Small Particles (Wiley, New York, 1983), pp. 475–482.
  11. M. Firbank, M. Oda, D. T. Delpy, Phys. Med. Biol. 40, 955 (1995). [CrossRef] [PubMed]
  12. S. J. Matcher, M. Cope, D. T. Delpy, “In vivo measurements of the wavelength dependence of tissue scattering coefficients between 760 and 900 nm measured with time-resolved spectroscopy,” Appl. Opt. (to be published).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1 Fig. 2 Fig. 3
 
Fig. 4
 

« Previous Article

OSA is a member of CrossRef.

CrossCheck Deposited