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Optics Letters

Optics Letters


  • Vol. 23, Iss. 10 — May. 15, 1998
  • pp: 810–812

Fluorescence lifetime imaging with picosecond resolution for biomedical applications

K. Dowling, M. J. Dayel, M. J. Lever, P. M. W. French, J. D. Hares, and A. K. L. Dymoke-Bradshaw  »View Author Affiliations

Optics Letters, Vol. 23, Issue 10, pp. 810-812 (1998)

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We describe a novel whole-field fluorescence lifetime imaging system, based on a time-gated image intensifier and a solid-state laser oscillator–amplifier, that images lifetime differences of less than 10 ps. This system was successfully applied to discrimination between biological tissue constituents.

© 1998 Optical Society of America

OCIS Codes
(140.7090) Lasers and laser optics : Ultrafast lasers
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(170.2520) Medical optics and biotechnology : Fluorescence microscopy
(170.3650) Medical optics and biotechnology : Lifetime-based sensing
(170.3880) Medical optics and biotechnology : Medical and biological imaging

K. Dowling, M. J. Dayel, M. J. Lever, P. M. W. French, J. D. Hares, and A. K. L. Dymoke-Bradshaw, "Fluorescence lifetime imaging with picosecond resolution for biomedical applications," Opt. Lett. 23, 810-812 (1998)

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