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Optics Letters

Optics Letters


  • Vol. 23, Iss. 11 — Jun. 1, 1998
  • pp: 879–881

Acoustically modulated speckle imaging of biological tissues

Steven L. Jacques and Sean J. Kirkpatrick  »View Author Affiliations

Optics Letters, Vol. 23, Issue 11, pp. 879-881 (1998)

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A video laser speckle imaging technique yields images with contrast based on the mechanical properties of a tissue. Fluctuations of laser speckle patterns induced by acoustically driving the tissue at various frequencies in the 0–30-Hz range encode the mechanical strain of the tissue. At each acoustic frequency and within the camera acquisition time, each camera pixel integrates a temporally fluctuating speckle intensity whose variance encodes the mechanical strain in response to the acoustic modulation. The magnitude and the frequency dependence of this strain provide mechanical information about the tissue and are the contrast mechanism for images.

© 1998 Optical Society of America

OCIS Codes
(030.6140) Coherence and statistical optics : Speckle
(110.6150) Imaging systems : Speckle imaging
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.0110) Medical optics and biotechnology : Imaging systems
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3880) Medical optics and biotechnology : Medical and biological imaging

Steven L. Jacques and Sean J. Kirkpatrick, "Acoustically modulated speckle imaging of biological tissues," Opt. Lett. 23, 879-881 (1998)

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