OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Vol. 24, Iss. 12 — Jun. 15, 1999
  • pp: 829–831

Noninvasive optical method of measuring tissue and arterial saturation: an application to absolute pulse oximetry of the brain

Maria Angela Franceschini, Enrico Gratton, and Sergio Fantini  »View Author Affiliations


Optics Letters, Vol. 24, Issue 12, pp. 829-831 (1999)
http://dx.doi.org/10.1364/OL.24.000829


View Full Text Article

Acrobat PDF (606 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We present a frequency-domain optical method for real-time noninvasive measurement of absolute tissue and arterial saturation. This method is based on quantitative measurement of the tissue absorption spectrum (for tissue saturation) and of the amplitude of the arterial-pulsation-induced absorption oscillations (for arterial saturation) at eight wavelengths in the range 633–841 nm. We report results obtained from readings taken from the forehead of a healthy volunteer, showing baseline saturation values of 74.7±0.2% (tissue) and 96.9±0.5% (arterial). These values dropped to minimum values of 71.6±0.2% and 90.0±0.2% , respectively, after 1 min of reduced inspired oxygen concentration [10% (by volume) O2 from a baseline value of 21% O2 ].

© 1999 Optical Society of America

OCIS Codes
(000.1430) General : Biology and medicine
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.5270) Medical optics and biotechnology : Photon density waves
(170.5280) Medical optics and biotechnology : Photon migration
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics

Citation
Maria Angela Franceschini, Enrico Gratton, and Sergio Fantini, "Noninvasive optical method of measuring tissue and arterial saturation: an application to absolute pulse oximetry of the brain," Opt. Lett. 24, 829-831 (1999)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-24-12-829


Sort:  Author  |  Year  |  Journal  |  Reset

References

  1. G. A. Millikan, Rev. Sci. Instrum. 13, 434 (1942).
  2. S. Fantini, M. A. Franceschini, J. S. Maier, S. A. Walker, B. Barbieri, and E. Gratton, Opt. Eng. 34, 32 (1995).
  3. M. Miwa, Y. Ueda, and B. Chance, Proc. SPIE 2389, 142 (1995).
  4. H. Liu, B. Chance, A. H. Hielscher, S. L. Jacques, and F. K. Tittel, Med. Phys. 22, 1209 (1995).
  5. M. Kohl, C. Nolte, H. R. Heekeren, S. Horst, U. Scholz, H. Obrig, and A. Villringer, Proc. SPIE 3194, 18 (1998).
  6. T. Aoyagi, M. Kishi, K. Yamaguchi, and S. Watanabe, in Abstracts of the Japanese Society of Medical Electronics and Biological Engineering (Japanese Society of Medical Electronics and Biological Engineering, Tokyo, 1974), p. 90.
  7. Y. Mendelson, Clin. Chem. (Winston-Salem, N.C.) 38, 1601 (1992).
  8. R. K. Webb, A. C. Ralston, and W. B. Runciman, Anaesthesia 46, 207 (1991).
  9. M. A. Franceschini, D. Wallace, B. Barbieri, S. Fantini, W. W. Mantulin, S. Pratesi, G. P. Donzelli, and E. Gratton, Proc. SPIE 2979, 807 (1997).
  10. D. M. Hueber, S. Fantini, A. E. Cerussi, and B. Barbieri, “New Optical probe designs for absolute (self-calibrating) NIR tissue hemoglobin measurements,” in Proc. SPIE 3597 (to be published).
  11. S. Fantini, M. A. Franceschini, and E. Gratton, J. Opt. Soc. Am. B 11, 2128 (1994).
  12. D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, and J. Wyatt, Phys. Med. Biol. 33, 1433 (1988).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited