Abstract
We present a frequency-domain optical method for real-time noninvasive measurement of absolute tissue and arterial saturation. This method is based on quantitative measurement of the tissue absorption spectrum (for tissue saturation) and of the amplitude of the arterial-pulsation-induced absorption oscillations (for arterial saturation) at eight wavelengths in the range 633–841 nm. We report results obtained from readings taken from the forehead of a healthy volunteer, showing baseline saturation values of (tissue) and (arterial). These values dropped to minimum values of and , respectively, after 1 min of reduced inspired oxygen concentration [10% (by volume) from a baseline value of 21% ].
© 1999 Optical Society of America
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