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Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Vol. 24, Iss. 19 — Oct. 1, 1999
  • pp: 1358–1360

Real-time in vivo imaging of human gastrointestinal ultrastructure by use of endoscopic optical coherence tomography with a novel efficient interferometer design

Andrew M. Rollins, Rujchai Ung-arunyawee, Amitabh Chak, Richard C. K. Wong, Kenji Kobayashi, Michael V. Sivak, Jr., and Joseph A. Izatt  »View Author Affiliations


Optics Letters, Vol. 24, Issue 19, pp. 1358-1360 (1999)
http://dx.doi.org/10.1364/OL.24.001358


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Abstract

We report on the design and initial clinical experience with a real-time endoscopic optical coherence tomography (EOCT) imaging system. The EOCT unit includes a high-speed optical coherence tomography interferometer, endoscope-compatible catheter probes, and real-time data capture and display hardware and software. Several technological innovations are introduced that improve EOCT efficiency and performance. In initial clinical studies using the EOCT system, the esophagus, stomach, duodenum, ileum, colon, and rectum of patients with normal endoscopic findings were examined. In these initial investigations, EOCT imaging clearly delineated the substructure of the mucosa and submucosa in several gastrointestinal organs; microscopic structures such as glands, blood vessels, pits, villi, and crypts were also observed.

© 1999 Optical Society of America

OCIS Codes
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.2680) Medical optics and biotechnology : Gastrointestinal
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

Citation
Andrew M. Rollins, Rujchai Ung-arunyawee, Amitabh Chak, Richard C. K. Wong, Kenji Kobayashi, Michael V. Sivak, Jr., and Joseph A. Izatt, "Real-time in vivo imaging of human gastrointestinal ultrastructure by use of endoscopic optical coherence tomography with a novel efficient interferometer design," Opt. Lett. 24, 1358-1360 (1999)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-24-19-1358

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