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Optics Letters

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  • Vol. 26, Iss. 11 — Jun. 1, 2001
  • pp: 822–824

Initial studies of in vivo absorbing and scattering heterogeneity in near-infrared tomographic breast imaging

Troy O. McBride, Brian W. Pogue, Shudong Jiang, Ulf L. Österberg, Keith D. Paulsen, and Steven P. Poplack  »View Author Affiliations


Optics Letters, Vol. 26, Issue 11, pp. 822-824 (2001)
http://dx.doi.org/10.1364/OL.26.000822


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Abstract

Simultaneously recovered absorption and scattering images that separate these optical property features within the female breast are demonstrated from frequency-domain measurements. A study of known absorbing and scattering objects is presented as a foundation for interpreting these in vivo images once the contrast space has been fully characterized. No measurable influence of absorbing-object contrast appears in the scattering images, whereas localized scattering contrast enhances the corresponding region within the absorption image by approximately 30% (e.g., a 2:1 scatterer also reconstructs as an ≈1.3:1 absorber). Scattering and absorption images of a female volunteer with a 3.4-cm fibroadenoma show a clear 2:1 localized increase in absorption coefficient with little or no evidence of scattering enhancement in the lesion.

© 2001 Optical Society of America

OCIS Codes
(110.3080) Imaging systems : Infrared imaging
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.6960) Medical optics and biotechnology : Tomography

Citation
Troy O. McBride, Brian W. Pogue, Shudong Jiang, Ulf L. Österberg, Keith D. Paulsen, and Steven P. Poplack, "Initial studies of in vivo absorbing and scattering heterogeneity in near-infrared tomographic breast imaging," Opt. Lett. 26, 822-824 (2001)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-26-11-822


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References

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