Simultaneously recovered absorption and scattering images that separate these optical property features within the female breast are demonstrated from frequency-domain measurements. A study of known absorbing and scattering objects is presented as a foundation for interpreting these in vivo images once the contrast space has been fully characterized. No measurable influence of absorbing-object contrast appears in the scattering images, whereas localized scattering contrast enhances the corresponding region within the absorption image by approximately 30% (e.g., a 2:1 scatterer also reconstructs as an ≈1.3:1 absorber). Scattering and absorption images of a female volunteer with a 3.4-cm fibroadenoma show a clear 2:1 localized increase in absorption coefficient with little or no evidence of scattering enhancement in the lesion.
© 2001 Optical Society of America
(110.3080) Imaging systems : Infrared imaging
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.6960) Medical optics and biotechnology : Tomography
Troy O. McBride, Brian W. Pogue, Shudong Jiang, Ulf L. Österberg, Keith D. Paulsen, and Steven P. Poplack, "Initial studies of in vivo absorbing and scattering heterogeneity in near-infrared tomographic breast imaging," Opt. Lett. 26, 822-824 (2001)