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Optics Letters

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  • Vol. 26, Iss. 23 — Dec. 1, 2001
  • pp: 1909–1911

Multimodal nonlinear spectral microscopy based on a femtosecond Cr:forsterite laser

Shi-Wei Chu, I-Hsiu Chen, Tzu-Ming Liu, Ping Chin Chen, Chi-Kuang Sun, and Bai-Ling Lin  »View Author Affiliations


Optics Letters, Vol. 26, Issue 23, pp. 1909-1911 (2001)
http://dx.doi.org/10.1364/OL.26.001909


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Abstract

We demonstrate a novel multimodal nonlinear spectral microscopy based on a femtosecond Cr:forsterite laser at 1230 nm. By acquiring the whole nonlinear spectrum in the visible and near-NIR region, this novel technique allows a combination of different imaging modalities, including second-harmonic generation, third-harmonic generation, and multiple-photon fluorescence. Combined with the selected excitation wavelength, which is located in the IR transparency window, this microscopic technique can provide high penetration depth with reduced damage and is ideal for studying living cells.

© 2001 Optical Society of America

OCIS Codes
(180.1790) Microscopy : Confocal microscopy
(190.7110) Nonlinear optics : Ultrafast nonlinear optics

Citation
Shi-Wei Chu, I-Hsiu Chen, Tzu-Ming Liu, Ping Chin Chen, Chi-Kuang Sun, and Bai-Ling Lin, "Multimodal nonlinear spectral microscopy based on a femtosecond Cr:forsterite laser," Opt. Lett. 26, 1909-1911 (2001)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-26-23-1909


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