Color Doppler optical coherence tomography (CDOCT) is a noninvasive optical imaging technique for micrometer-scale physiological flow mapping simultaneously with morphological optical coherence tomography imaging. We have developed a novel CDOCT signal-processing strategy capable of imaging physiological flow rates at 8 frames/s. Our new strategy features hardware-implemented digital autocorrelation across subsequent scans, permitting us to measure 300-Hz–8-kHz Doppler shifts upon signals of 0.6-MHz bandwidth. The performance of the CDOCT system was demonstrated in a flow phantom and <i>in vivo in Xenopus laevis</i>.
© 2002 Optical Society of America
(100.5070) Image processing : Phase retrieval
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
Volker Westphal, Siavash Yazdanfar, Andrew M. Rollins, and Joseph A. Izatt, "Real-time, high velocity-resolution color Doppler optical coherence tomography," Opt. Lett. 27, 34-36 (2002)