OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Vol. 27, Iss. 20 — Oct. 15, 2002
  • pp: 1800–1802

Submicrometer axial resolution optical coherence tomography

B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. St. J. Russell, M. Vetterlein, and E. Scherzer  »View Author Affiliations


Optics Letters, Vol. 27, Issue 20, pp. 1800-1802 (2002)
http://dx.doi.org/10.1364/OL.27.001800


View Full Text Article

Acrobat PDF (591 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

Optical coherence tomography (OCT) with unprecedented submicrometer axial resolution achieved by use of a photonic crystal fiber in combination with a compact sub-10-fs Ti:sapphire laser (Femtolasers Produktions) is demonstrated for what the authors believe is the first time. The emission spectrum ranges from 550 to 950 nm (λc=725 nm , Pout=27 mW) , resulting in a free-space axial OCT resolution of ~0.75 μm , corresponding to ~0.5 μm in biological tissue. Submicrometer-resolution OCT is demonstrated in vitro on human colorectal adenocarcinoma cells HT-29. This novel light source has great potential for development of spectroscopic OCT because its spectrum covers the absorption bands of several biological chromophores.

© 2002 Optical Society of America

OCIS Codes
(060.7140) Fiber optics and optical communications : Ultrafast processes in fibers
(110.4500) Imaging systems : Optical coherence tomography
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(190.4370) Nonlinear optics : Nonlinear optics, fibers

Citation
B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. St. J. Russell, M. Vetterlein, and E. Scherzer, "Submicrometer axial resolution optical coherence tomography," Opt. Lett. 27, 1800-1802 (2002)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-27-20-1800


Sort:  Author  |  Year  |  Journal  |  Reset

References

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
  2. J. G. Fujimoto, M. E. Brezinski, G. J. Tearney, S. A. Boppart, B. Bouma, M. R. Hee, J. F. Southern, and E. A. Swanson, Nature Med. 1, 970 (1995).
  3. A. F. Fercher, J. Biomed. Opt. 1, 157 (1996).
  4. X. Clivaz, F. Marquis-Weible, and R. P. Salathé, Electron. Lett. 28, 1553 (1994).
  5. A. F. Fercher, C. K. Hitzenberger, M. Sticker, E. Morena-Barriuso, R. Leitgeb, W. Drexler, and H. Sattmann, Opt. Commun. 185, 57 (2000).
  6. L. Vabre, A. Dubois, and C. Boccara, Opt. Lett. 27, 530 (2002).
  7. W. Drexler, U. Morgner, F. X. Kärtner, C. Pitris, S. A. Boppart, X. D. Li, E. P. Ippen, and J. G. Fujimoto, Opt. Lett. 24, 1221 (1999).
  8. W. Drexler, U. Morgner, R. K. Ghanta, J. S. Schuman, F. Kärtner, and J. G. Fujimoto, Nature Med. 7, 502 (2001).
  9. U. Morgner, W. Drexler, F. X. Kärtner, X. D. Li, C. Pitris, E. P. Ippen, and J. G. Fujimoto, Opt. Lett. 25, 111 (2000).
  10. J. K. Ranka, R. S. Windeler, and A. J. Stentz, Opt. Lett. 25, 25 (2000).
  11. T. A. Birks, W. J. Wadsworth, and P. St. J. Russell, Opt. Lett. 25, 1415 (2000).
  12. I. Hartl, X. D. Li, C. Chudoba, R. K. Ghanta, T. K. Ko, J. G. Fujimoto, J. K. Ranka, and P. S. Windeler, Opt. Lett. 26, 608 (2001).
  13. A. Apolonski, B. Povazay, A. Unterhuber, T. A. Birks, W. J. Wadsworth, P. St. J. Russell, and W. Drexler, J. Opt. Soc. Am. B 19, 2165 (2002).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited