OSA's Digital Library

Optics Letters

Optics Letters


  • Vol. 27, Iss. 4 — Feb. 15, 2002
  • pp: 246–248

Diffuse-reflectance spectroscopy from 500 to 1060 nm by correction for inhomogeneously distributed absorbers

R. L. P. van Veen, W. Verkruysse, and H. J. C. M. Sterenborg  »View Author Affiliations

Optics Letters, Vol. 27, Issue 4, pp. 246-248 (2002)

View Full Text Article

Acrobat PDF (85 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



Diffuse-reflectance spectroscopy for measurement of the absorption and scattering coefficients of biological tissue produces reliable results for wavelengths from 650 to 1050 nm. Implicitly, this approach assumes homogeneously distributed absorbers. A correction factor is introduced for inhomogeneous distribution of blood concentrated in discrete cylindrical vessels. This factor extends the applicability of diffusion theory to lower wavelengths. We present measurements of in vivo optical properties in the wavelength range 500–1060 nm.

© 2002 Optical Society of America

OCIS Codes
(160.4760) Materials : Optical properties
(170.3660) Medical optics and biotechnology : Light propagation in tissues

R. L. P. van Veen, W. Verkruysse, and H. J. C. M. Sterenborg, "Diffuse-reflectance spectroscopy from 500 to 1060 nm by correction for inhomogeneously distributed absorbers," Opt. Lett. 27, 246-248 (2002)

Sort:  Author  |  Year  |  Journal  |  Reset


  1. T. J. Farrell, M. S. Patterson, and B. C. Wilson, Med. Phys. 19, 879 (1992).
  2. A. Kienle and M. S. Patterson, J. Opt. Soc. Am. A 4, 246 (1997).
  3. R. M. P. Doornbos, R. Lang, M. C. Aalders, F. W. Cross, and H. J. C. M. Sterenborg, Phys. Med. Biol. 44, 967 (1999).
  4. A. M. K. Nilsson, C. Sturesson, D. L. Liu, and S. Andersson-Engels, Appl. Opt. 37, 1256 (1997).
  5. N. Dognitz and G. Wagnieres, Lasers Med. Sci. 13, 55 (1998).
  6. A. Torricelli, A. Pifferi, P. Taroni, E. Giambattistelli, and R. Cubeddu, Phys. Med. Biol. 46, 2227 (2001).
  7. R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and D. Valentini, Appl. Phys. Lett. 74, 874 (1999).
  8. K. Furutsu, J. Opt. Soc. Am. 70, 360 (1980).
  9. M. Firbank, E. Okada, and D. T. Delpy, Phys. Med. Biol. 42, 465 (1997).
  10. A. Talsma, B. Chance, and R. Graaff, J. Opt. Soc. Am. 4, 932 (2001).
  11. H. Liu, B. Chance, A. H. Hielscher, S. L. Jacques, and F. K. Tittel, Med. Phys. 22, 1209 (1995).
  12. W. Verkruysse, G. W. Lucassen, J. F. de Boer, D. J. Smithies, J. S. Nelson, and M. J. C. van Gemert, Phys. Med. Biol. 42, 51 (1997).
  13. L. O. Svaasand, E. J. Fiskerstrand, G. Kopstad, L. T. Norvang, E. K. Svaasand, J. S. Nelson, and M. W. Berns, Lasers Med. Sci. 10, 235 (1995).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited