Optical tomography of turbid media has so far been limited by systems that require fixed geometries or measurements employing fibers. We present a system that records noncontact optical measurements from diffuse media of arbitrary shapes and retrieves the three-dimensional surface information of the diffuse medium. We further present a novel method of combining this composite data set and obtain accurate fluorescence reconstructions. This approach offers significant experimental simplicity and yields high-information-content datasets. The performance of this novel tomographic approach is demonstrated with experimental reconstructions of phantoms.
© 2003 Optical Society of America
Ralf B. Schulz, Jorge Ripoll, and Vasilis Ntziachristos, "Noncontact optical tomography of turbid media," Opt. Lett. 28, 1701-1703 (2003)