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Optics Letters

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  • Vol. 28, Iss. 2 — Jan. 15, 2003
  • pp: 120–122

Selective detection of fluorophore layers in turbid media: the role of fiber-optic probe design

T. Joshua Pfefer, L. Stephanie Matchette, Amanda M. Ross, and Marwood N. Ediger  »View Author Affiliations


Optics Letters, Vol. 28, Issue 2, pp. 120-122 (2003)
http://dx.doi.org/10.1364/OL.28.000120


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Abstract

Experimental verification of the ability to alter the sensitivity to fluorophore layers in turbid media by varying illumination-collection geometry is presented. Fiber-optic probes and two-layer, fluorophore-doped, turbid phantoms are used to elucidate the roles of spot size, illumination–collection fiber separation, and probe–sample spacing. Variations in single- and multiple-fiber probe design parameters produce significant changes in the relative sensitivity to sample layers in a manner that agrees with prior computational studies.

© 2003 Optical Society of America

OCIS Codes
(060.2370) Fiber optics and optical communications : Fiber optics sensors
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence

Citation
T. Joshua Pfefer, L. Stephanie Matchette, Amanda M. Ross, and Marwood N. Ediger, "Selective detection of fluorophore layers in turbid media: the role of fiber-optic probe design," Opt. Lett. 28, 120-122 (2003)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-28-2-120


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References

  1. G. A. Wagnieres, W. M. Star, and B. C. Wilson, Photochem. Photobiol. 68, 603 (1998).
  2. A. J. Welch, C. Gardner, R. Richards-Kortum, E. Chan, G. Criswell, J. Pfefer, and S. Warren, Lasers Surg. Med. 21, 166 (1997).
  3. T. J. Pfefer, K. T. Schomacker, M. N. Ediger, and N. S. Nishioka, IEEE J. Sel. Top. Quantum Electron. 7, 1004 (2001).
  4. T. J. Pfefer, K. T. Schomacker, M. N. Ediger, and N. S. Nishioka, Appl. Opt. 41, 4712 (2002).
  5. R. Drezek, K. Sokolov, U. Utzinger, I. Boiko, A. Malpica, M. Follen, and R. Richards-Kortum, J. Biomed. Opt. 6, 385 (2001).
  6. E. L. Hull, M. G. Nichols, and T. H. Foster, Appl. Opt. 37, 2755 (1998).
  7. D. E. Hyde, T. J. Farrell, M. S. Patterson, and B. C. Wilson, Phys. Med. Biol. 46, 269 (2001).
  8. L. Quan and N. Ramanujam, Opt. Lett. 27, 104 (2002).
  9. G. Wagnieres, S. Cheng, M. Zellweger, N. Utke, D. Braichotte, J. P. Ballini, and H. van den Bergh, Phys. Med. Biol. 42, 1415 (1997).

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