Dual-axes confocal microscopy with post-objective scanning and low-coherence heterodyne detection
Optics Letters, Vol. 28, Issue 20, pp. 1915-1917 (2003)
http://dx.doi.org/10.1364/OL.28.001915
Acrobat PDF (3190 KB)
Abstract
We present a dual-axes confocal microscope that employs postobjective scanning and low-coherence heterodyne detection to collect vertical cross-sectional images from biological tissue with high axial resolution, reduced noise from scattered light, deep tissue penetration, and a large dynamic range. This architecture can be scaled down to millimeter dimensions with microelectromechanical systems technology for performance of in vivo optical biopsy.
© 2003 Optical Society of America
OCIS Codes
(110.0180) Imaging systems : Microscopy
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(120.4570) Instrumentation, measurement, and metrology : Optical design of instruments
(170.1790) Medical optics and biotechnology : Confocal microscopy
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.4730) Medical optics and biotechnology : Optical pathology
Citation
Thomas D. Wang, Christopher H. Contag, Michael J. Mandella, NingY. Chan, and Gordon S. Kino, "Dual-axes confocal microscopy with post-objective scanning and low-coherence heterodyne detection," Opt. Lett. 28, 1915-1917 (2003)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-28-20-1915
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