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Optics Letters

Optics Letters


  • Vol. 28, Iss. 21 — Nov. 1, 2003
  • pp: 2061–2063

Volumetric diffuse optical tomography of brain activity

Joseph P. Culver, Andrew M. Siegel, Jonathan J. Stott, and David A. Boas  »View Author Affiliations

Optics Letters, Vol. 28, Issue 21, pp. 2061-2063 (2003)

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We present three-dimensional diffuse optical tomography of the hemodynamic response to somatosensory stimulation in a rat. These images show the feasibility of volumetrically imaging the functional response to brain activity with diffuse light. A combination of positional optode calibration and contrast-to-noise ratio weighting was found to improve imaging performance.

© 2003 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5270) Medical optics and biotechnology : Photon density waves
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics

Joseph P. Culver, Andrew M. Siegel, Jonathan J. Stott, and David A. Boas, "Volumetric diffuse optical tomography of brain activity," Opt. Lett. 28, 2061-2063 (2003)

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