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  • Vol. 28, Iss. 22 — Nov. 15, 2003
  • pp: 2204–2206

Effect of surface roughness on determination of bulk tissue optical parameters

Xiaoyan Ma, Jun Qing Lu, and Xin-Hua Hu  »View Author Affiliations


Optics Letters, Vol. 28, Issue 22, pp. 2204-2206 (2003)
http://dx.doi.org/10.1364/OL.28.002204


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Abstract

Monte Carlo simulations have been conducted to investigate the effect of surface roughness on the inverse determination of bulk optical parameters. Results show that μs , μa , and g can be overestimated by an order of magnitude for thin slab tissue samples with a moderate index mismatch at the interfaces if typical surface roughness is neglected. Measurements of Intralipid samples between glass windows with smooth and rough surfaces have been carried out and agreement was found between the numerical and the experimental data. This study suggests that the surface roughness should be taken into account for both in vitro and in vivo determination of bulk tissue optical parameters.

© 2003 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.4730) Medical optics and biotechnology : Optical pathology
(290.5880) Scattering : Scattering, rough surfaces

Citation
Xiaoyan Ma, Jun Qing Lu, and Xin-Hua Hu, "Effect of surface roughness on determination of bulk tissue optical parameters," Opt. Lett. 28, 2204-2206 (2003)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-28-22-2204


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