We have developed an ultrahigh-resolution optical coherence tomographic system in which broadband continuum generation from a photonic crystal fiber is used to produce high longitudinal resolution. Longitudinal resolution of 1.3-μm has been achieved in a biological tissue by use of continuum light from 800 to 1400 nm. The system employed a dynamic-focusing tracking method to maintain high lateral resolution over a large imaging depth. Subcellular imaging is demonstrated.
© 2003 Optical Society of America
(170.4500) Medical optics and biotechnology : Optical coherence tomography
Yimin Wang, Yonghua Zhao, J. S. Nelson, Zhongping Chen, and Robert S. Windeler, "Ultrahigh-resolution optical coherence tomography by broadband continuum generation from a photonic crystal fiber," Opt. Lett. 28, 182-184 (2003)