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Optics Letters

Optics Letters

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  • Vol. 28, Iss. 8 — Apr. 15, 2003
  • pp: 625–627

Electro-optic response of second-harmonic generation membrane potential sensors

L. Moreaux, T. Pons, V. Dambrin, M. Blanchard-Desce, and J. Mertz  »View Author Affiliations


Optics Letters, Vol. 28, Issue 8, pp. 625-627 (2003)
http://dx.doi.org/10.1364/OL.28.000625


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Abstract

We quantify and ascertain the nature of the second-harmonic generation (SHG) response of amphiphilic push–pull chromophores to a transmembrane electric field. Our technique is based on the application of an alternating field across labeled giant unilamelar vesicles. For chromophore responses that are purely electro-optic, our technique provides an estimate of photoinduced charge shifts based on the observed dispersion of the field response, in accord with a two-level perturbation theory. These results are applicable to the optimization of membrane potential sensors for SHG microscopy.

© 2003 Optical Society of America

OCIS Codes
(180.0180) Microscopy : Microscopy
(190.4710) Nonlinear optics : Optical nonlinearities in organic materials

Citation
L. Moreaux, T. Pons, V. Dambrin, M. Blanchard-Desce, and J. Mertz, "Electro-optic response of second-harmonic generation membrane potential sensors," Opt. Lett. 28, 625-627 (2003)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-28-8-625

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