A novel, compact, user friendly fiber laser with a broad emission bandwidth (MenloSystems, λc=1375nm, Δλ=470nm, Pout=4mW) was used to achieve unprecedented sub-2-μm axial resolution optical coherence tomography (OCT) in nontransparent biological tissue in the 1300-nm wavelength region. Fresh human skin and arterial biopsies were imaged ex vivo with ~1.4-μm axial and ~3-μm lateral resolution and 95-dB sensitivity, demonstrating the great potential for clinical OCT applications of this stable, low-cost, and turn-on-key fiber laser.
© 2003 Optical Society of America
(140.3510) Lasers and laser optics : Lasers, fiber
(170.1650) Medical optics and biotechnology : Coherence imaging
(170.1870) Medical optics and biotechnology : Dermatology
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
K. Bizheva, B. Považay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-μm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003)