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Optics Letters

Optics Letters


  • Vol. 29, Iss. 1 — Jan. 1, 2004
  • pp: 83–85

Group index of the human cornea at 1.3- m m wavelength obtained in vitro by optical coherence domain reflectometry

Roger C. Lin, Mark A. Shure, Andrew M. Rollins, Joseph A. Izatt, and David Huang  »View Author Affiliations

Optics Letters, Vol. 29, Issue 1, pp. 83-85 (2004)

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The group index of the cornea, rather than the phase refractive index, is required for thickness calculations with optical coherence tomography. Recent advances with high-speed optical coherence tomography at 1.3 μm make index measurement at this wavelength of great interest. Group indices of three human corneas from an eye bank were measured in vitro with optical coherence domain reflectometry. Measurements were made in a calibrated cuvette filled with a preservation medium to maintain proper corneal hydration. Group indices were calculated from the optical path lengths measured. The corneal group index was 1.389 ± 0.004 (average ± standard deviation). The average group index of a balanced salt solution, an approximation to aqueous humor, was 1.343 ± 0.001 .

© 2004 Optical Society of America

OCIS Codes
(170.1420) Medical optics and biotechnology : Biology
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.6930) Medical optics and biotechnology : Tissue

Roger C. Lin, Mark A. Shure, Andrew M. Rollins, Joseph A. Izatt, and David Huang, "Group index of the human cornea at 1.3- m m wavelength obtained in vitro by optical coherence domain reflectometry," Opt. Lett. 29, 83-85 (2004)

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  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
  2. C. Wirbelauer, C. Scholz, H. Hoerauf, R. Engelhardt, R. Birngruber, and H. Laqua, Am. J. Ophthalmol. 130, 693 (2000).
  3. M. Born and E. Wolf, Principles of Optics (Cambridge U. Press, Cambridge, England, 1999).
  4. I. R. Schwab, R. J. Epstein, D. J. Harris, Jr., S. C. Pflugfelder, and K. R. Wilhelmus, in Basic and Clinical Science Course: External Disease and Cornea, Section 8, M. Denny, ed. (American Academy of Ophthalmology, San Francisco, Calif., 2002).
  5. S. Muscat, N. McKay, S. Parks, E. Kemp, and D. Keating, Invest. Ophthalmol. Visual Sci. 43, 1791 (2002).
  6. M. J. Maldonado, L. Ruiz-Oblitas, J. M. Munuera, D. Aliseda, A. Garcia-Layana, and J. Moreno-Montanes, Ophthalmology 107, 81 (2000).
  7. J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Arch. Ophthalmol. 112, 1584 (1994).
  8. C. K. Hitzenberger, A. Baumgartner, W. Drexler, and A. F. Fercher, Am. J. Ophthalmol. 118, 468 (1994).
  9. W. Drexler, C. K. Hitzenberger, A. Baumgartner, O. Findl, H. Sattmann, and A. F. Fercher, Exp. Eye. Res. 66, 25 (1998).
  10. S. R. Uhlhorn, F. Manns, H. Tahi, P. Rol, and J. Parel, Proc. SPIE 3246, 14 (1998).
  11. S. Radhakrisnan, A. M. Rollins, J. E. Roth, S. Yazdanfar, V. Westphal, D. S. Bardenstain, and J. A. Izatt, Arch. Ophthalmol. 119, 1179 (2001).
  12. M. Ohmi, Y. Ohnishi, K. Yoden, and M. Haruna, IEEE Trans. Biomed. Eng. 47, 1266 (2000).
  13. D. R. Lide, ed., CRC Handbook of Chemistry and Physics (CRC Press, Ann Arbor, Mich., 1994).
  14. M. J. Doughty and M. L. Zaman, Surv. Ophthalmol. 44, 367 (2000).
  15. C. K. Hitzenberger, Invest. Ophthalmol. Visual Sci. 32, 616 (1991).
  16. H. Obstfeld, Optics in Vision (Butterworth, London, 1982), p. 30.
  17. S. Patel, J. Marshall, and F. W. Fitzke, J. Refract. Surg. 11, 100 (1995).
  18. A. H. Harvey, J. S. Gallagher, and J. M. H. Levelt Senger, J. Phys. Chem. Ref. Data. 27, 761 (1998).

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