OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Vol. 29, Iss. 17 — Sep. 1, 2004
  • pp: 2010–2012

Fluorescence polarization imaging for delineating nonmelanoma skin cancers

A. N. Yaroslavsky, V. Neel, and R. R. Anderson  »View Author Affiliations


Optics Letters, Vol. 29, Issue 17, pp. 2010-2012 (2004)
http://dx.doi.org/10.1364/OL.29.002010


View Full Text Article

Acrobat PDF (3153 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We present a method for detecting nonmelanoma skin cancers using exogenous fluorescence polarization. We built an automated system that permits exogenous fluorescence polarization imaging. It includes a tunable linearly polarized monochromatic light source and a CCD camera equipped with a rotating linear polarizer and a filter to reject excitation light. Two fluorophores that are retained in tumors, toluidine blue and methylene blue, are employed. We demonstrate that fluorescence polarization imaging can be used for accurate delineation of nonmelanoma cancers. The results suggest that this optical technique may be suitable for real-time noninvasive demarcation of epithelial cancers.

© 2004 Optical Society of America

OCIS Codes
(170.1870) Medical optics and biotechnology : Dermatology
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4730) Medical optics and biotechnology : Optical pathology
(170.6480) Medical optics and biotechnology : Spectroscopy, speckle

Citation
A. N. Yaroslavsky, V. Neel, and R. R. Anderson, "Fluorescence polarization imaging for delineating nonmelanoma skin cancers," Opt. Lett. 29, 2010-2012 (2004)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-29-17-2010

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited